Monday, February 28, 2011

Varicose Veins

Varicose Veins

  • Definition :
    • Varicose Veins Are Dilated, Tortuous Superficial Veins
    • They Can Occur As An Isolated FIndings Or Can Be A Manifestation Of Underlying Venous Insufficiency


  • Epidemiology :
    • Prevalence : 15 - 20 % Of Adults
    • Sex : 2 - 3 Times As Frequent In Women As In Men
  • Risk Factors :
    • Positive Family History Of Varicose Veins
      • Positive In Half Of Patients With Primary Varicose Veins
      • If Both Parents Have Varicose Veins, The Risk Is Around 90%
    • Female Sex
    • Increasing Age
    • Pregnancy
    • Obesity
    • Prolonged Standing
  • Etiology :
    • Various Causes Including :
      • Defective Structure And Function Of The Valves Of The Saphenous Veins
      • Intrinsic Weakness Of The Vein Wall
      • High Intraluminal Pressure
      • Arteriovenous Fistulae (RARELY)


  • Classification :
    • Primary Varicose Veins
      • Originate In The Superficial System
    • Secondary Varicose Veins
      • Deep Venous Insufficiency And Incompetent Perforating Veins
      • Deep Venous Occlusion Causing Enlargement Of Superficial Veins Serving As Collaterals
  • Diagnosis :
    • Sign & Symptoms :
      • Asymptomatic - MOST COMMON
      • Dull Ache Or Pressure Sensation In The Legs After Prolonged Standing, Which Relieved With Leg Elevation
      • Legs Feel Heavy
      • Cramping
      • Muscle Fatigue
      • Pruritus
      • Mild Ankle Edema
      • Visible, Palpable, Dilated, Tortuous, Superficial Veins
        • Mainly In The Lower Extremities
        • Generally > 3 mm In Diameter
    • Imaging :
      • Duplex Ultrasonography
        • Non Invasive Imaging Often Used Prior To Ablative Or Operative Procedure
      • Magnetic Resonance Venography
        • Most Sensitive And Specific Test To Locate Anatomic Obstruction
        • Reserved For Difficult Cases, Rarely Required
  • Treatment :
    • Supportive :
      • Purpose : Alleviation Of Symptoms
      • Weight Loss, Elevate Legs Periodically, Avoid Prolonged Standing,
      • Wear Elastic Support Hose
        • Start With Low Pressure Stockings (Class I, 20 - 30 mmHg)
        • And Progress To Higher Pressure Stockings Only If Symptoms So Dictate
        • Main Side Effects : SKIN IRRITATION & CONTACT DERMATITIS
    • Ablative Procedures :
      • Sclerotherapy
        • Generally Used To Treat Small, Symptomatic Varicose Veins
        • Procedure Is Done With No Or Only Local Anesthesia
        • Sclerosing Solution Is Injected Into The Involved Varicose Vein
          • Solution Damages The Endothelium Leading To Thrombosis And Inability Of The Vein To Fill
        • A Compression Bandage Is Applied
        • Contraindications :
          • Varicosities Of More Than 6 mm, Arterial Insufficiency Of The Legs, Anticoagulation, Hypercoagulable States, Phlebitis, Pregnancy, Any Disease That Will Hamper Post Surgical Ambulation, Morbid Obesity
      • Endovenous Radiofrequency Or Laser Ablation
        • Percutaneous, Endovenous Delivery Of Radiofrequency Or Laser Energy Can Be Used To Treat Incompetent Greater Saphenous Veins


    • Surgical Therapy
      • Usually Involves Extensive Ligation And Stripping Of The Greater And Lesser Saphenous Veins
  • Complications :
    • Pigmentation
    • Skin Ulceration
    • Superimposed Infection
    • Superficial Venous Thrombosis
    • Rupture WIth Bleeding / Hemorrhage (Rare)
  • Prognosis :
    • Course Is Chronic
    • Recurrence May Occur After Treatment
      • Over 5 Years, About 2 / 3 Of Patients WIll Experience Recurrence After Sclerotherapy
      • Recurrence Rate Is Lower After Ligation And Striping
  • Prevention :
    • NO KNOWN PRIMARY PREVENTION

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